Event Details
Abstract
Cancer is one of the leading causes of death worldwide and is well known for its complexity. Cancer cells within the same tumor or from different tumors are highly heterogeneous. Furthermore, stromal and immune cells within tumor microenvironment interact with cancer cells to play important roles in how tumor progress and respond to different treatments. Recent advances in single cell technologies, especially massively parallel single cell sequencing, have made it possible to analyze cancer cells and cells in its tumor microenvironment in parallel with unprecedented high resolution. We will summarize recent developments in single cell sequencing technologies and their applications in cancer research, and explain how insights generated from single cell sequencing can be used to develop novel diagnostic and therapeutic approaches to conquer cancer.
癌症是世界上主要的死亡原因之一，复杂性众所周知，来自不同肿瘤甚至同一肿瘤内的不同肿瘤细胞是高度异质的。并且肿瘤微环境中的基质细胞和免疫细胞与肿瘤细胞之间存在相互作用，在肿瘤进展和对不同治疗的反应中发挥重要作用。
现阶段单细胞技术发展迅猛，特别是大规模并行的单细胞测序为分析肿瘤细胞及肿瘤微环境中的细胞提供了前所未有的高分辨率。本次讲座将总结单细胞测序技术的最新发展及其在癌症研究中的应用，并探讨如何利用单细胞测序产生的结果指导新的诊断和治疗方法开发，从而战胜癌症。
